UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
WASHINGTON, DC 20549
FORM 10-Q
(Mark One)
☒ |
QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
For the quarterly period ended June 30, 2020
OR
☐ |
TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 |
For the transition period from _______ to _______
Commission File Number: 001-38853
NGM BIOPHARMACEUTICALS, INC.
(Exact Name of Registrant as Specified in its Charter)
Delaware |
26-1679911 |
(State or other jurisdiction of incorporation or organization) |
(I.R.S. Employer |
333 Oyster Point Boulevard South San Francisco, CA |
94080 |
(Address of principal executive offices) |
(Zip Code) |
Registrant’s telephone number, including area code: (650) 243-5555
Securities registered pursuant to Section 12(b) of the Act:
Title of Each Class of Securities Registered |
Trading Symbol |
Name of Each Exchange on which Securities are Registered |
Common Stock, par value $0.001 per share |
NGM |
The Nasdaq Stock Market LLC |
Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days. Yes ☒ No ☐
Indicate by check mark whether the registrant has submitted electronically every Interactive Data File required to be submitted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit such files). Yes ☒ No ☐
Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, smaller reporting company, or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,” “smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.
Large accelerated filer |
☐ |
|
Accelerated filer |
☐ |
Non-accelerated filer |
☒ |
|
Smaller reporting company |
☐ |
Emerging growth company |
☒ |
|
|
|
If an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying with any new or revised financial accounting standards provided pursuant to Section 13(a) of the Exchange Act. ☐
Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act). Yes ☐ No ☒
As of August 7, 2020, the registrant had 68,827,752 shares of common stock, $0.001 par value per share, outstanding.
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Page |
PART I. |
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1 |
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Item 1. |
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1 |
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1 |
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2 |
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3 |
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4 |
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5 |
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6 |
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Notes to Condensed Consolidated Financial Statements (Unaudited) |
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7 |
Item 2. |
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Management’s Discussion and Analysis of Financial Condition and Results of Operations |
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26 |
Item 3. |
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38 |
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Item 4. |
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38 |
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PART II. |
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39 |
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Item 1. |
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39 |
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Item 1A. |
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39 |
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Item 2. |
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89 |
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Item 3. |
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89 |
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Item 4. |
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89 |
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Item 5. |
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89 |
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Item 6. |
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90 |
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91 |
i
NGM BIOPHARMACEUTICALS, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(In thousands, except share amounts)
(Unaudited)
|
|
June 30, |
|
|
December 31, |
|
||
|
|
2020 |
|
|
2019* |
|
||
Assets |
|
|
|
|
|
|
|
|
Current assets: |
|
|
|
|
|
|
|
|
Cash and cash equivalents |
|
$ |
249,317 |
|
|
$ |
245,598 |
|
Short-term marketable securities |
|
|
62,778 |
|
|
|
98,913 |
|
Related party receivable from collaboration |
|
|
3,079 |
|
|
|
5,206 |
|
Prepaid expenses and other current assets |
|
|
7,448 |
|
|
|
5,531 |
|
Total current assets |
|
|
322,622 |
|
|
|
355,248 |
|
Property and equipment, net |
|
|
17,321 |
|
|
|
19,475 |
|
Restricted cash |
|
|
1,874 |
|
|
|
1,874 |
|
Other non-current assets |
|
|
5,467 |
|
|
|
3,806 |
|
Total assets |
|
$ |
347,284 |
|
|
$ |
380,403 |
|
Liabilities and stockholders' equity |
|
|
|
|
|
|
|
|
Current liabilities: |
|
|
|
|
|
|
|
|
Accounts payable |
|
$ |
1,934 |
|
|
$ |
9,026 |
|
Accrued liabilities |
|
|
26,792 |
|
|
|
22,991 |
|
Deferred rent, current |
|
|
2,902 |
|
|
|
2,829 |
|
Deferred revenue, current |
|
|
2,074 |
|
|
|
4,872 |
|
Total current liabilities |
|
|
33,702 |
|
|
|
39,718 |
|
Deferred rent, non-current |
|
|
7,941 |
|
|
|
9,392 |
|
Other non-current liabilities |
|
|
4,188 |
|
|
|
— |
|
Early exercise stock option liability |
|
|
289 |
|
|
|
574 |
|
Total liabilities |
|
|
46,120 |
|
|
|
49,684 |
|
Commitments and contingencies (Note 6) |
|
|
|
|
|
|
|
|
Stockholders' equity: |
|
|
|
|
|
|
|
|
Preferred stock, $0.001 par value; 10,000,000 shares authorized; no shares issued or outstanding as of June 30, 2020 and December 31, 2019, respectively |
|
|
— |
|
|
|
— |
|
Common stock, $0.001 par value; 400,000,000 shares authorized; 68,739,866 and 66,960,279 shares issued and outstanding as of June 30, 2020 and December 31, 2019, respectively |
|
|
69 |
|
|
|
67 |
|
Additional paid-in capital |
|
|
541,833 |
|
|
|
526,771 |
|
Accumulated other comprehensive gain |
|
|
137 |
|
|
|
25 |
|
Accumulated deficit |
|
|
(240,875 |
) |
|
|
(196,144 |
) |
Total stockholders' equity |
|
|
301,164 |
|
|
|
330,719 |
|
Total liabilities and stockholders' equity |
|
$ |
347,284 |
|
|
$ |
380,403 |
|
See accompanying notes to unaudited condensed consolidated financial statements.
*The condensed consolidated balance sheet as of December 31, 2019 has been derived from the audited financial statements as of that date.
1
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS
(In thousands, except share and per share amounts)
(Unaudited)
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
||||||||||
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June 30, |
|
|
June 30, |
|
||||||||||
|
|
|
2020 |
|
|
2019 |
|
|
2020 |
|
|
2019 |
|
||||
Related party revenue |
|
|
$ |
19,755 |
|
|
$ |
25,341 |
|
|
$ |
44,119 |
|
|
$ |
50,893 |
|
Operating expenses: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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Research and development |
|
|
|
38,494 |
|
|
|
28,819 |
|
|
|
76,933 |
|
|
|
58,346 |
|
General and administrative |
|
|
|
6,794 |
|
|
|
6,229 |
|
|
|
13,389 |
|
|
|
11,596 |
|
Total operating expenses |
|
|
|
45,288 |
|
|
|
35,048 |
|
|
|
90,322 |
|
|
|
69,942 |
|
Loss from operations |
|
|
|
(25,533 |
) |
|
|
(9,707 |
) |
|
|
(46,203 |
) |
|
|
(19,049 |
) |
Interest income |
|
|
|
388 |
|
|
|
2,044 |
|
|
|
1,563 |
|
|
|
3,154 |
|
Other expense, net |
|
|
|
(471 |
) |
|
|
(6 |
) |
|
|
(91 |
) |
|
|
(42 |
) |
Net loss |
|
|
$ |
(25,616 |
) |
|
$ |
(7,669 |
) |
|
$ |
(44,731 |
) |
|
$ |
(15,937 |
) |
Net loss per share, basic and diluted |
|
|
$ |
(0.38 |
) |
|
$ |
(0.13 |
) |
|
$ |
(0.66 |
) |
|
$ |
(0.47 |
) |
Weighted average shares used to compute net loss per share, basic and diluted |
|
|
|
68,305,056 |
|
|
|
61,044,450 |
|
|
|
67,850,640 |
|
|
|
34,078,099 |
|
See accompanying notes to unaudited condensed consolidated financial statements.
2
CONDENSED CONSOLIDATED STATEMENTS OF COMPREHENSIVE LOSS
(In thousands)
(Unaudited)
|
|
|
Three Months Ended |
|
|
Six Months Ended |
|
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June 30, |
|
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June 30, |
|
||||||||||
|
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2020 |
|
|
2019 |
|
|
2020 |
|
|
2019 |
|
||||
Net loss |
|
|
$ |
(25,616 |
) |
|
$ |
(7,669 |
) |
|
$ |
(44,731 |
) |
|
$ |
(15,937 |
) |
Other comprehensive gain (loss), net of tax: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Net unrealized gain on available-for-sale marketable securities |
|
|
|
192 |
|
|
|
147 |
|
|
|
112 |
|
|
|
369 |
|
Total comprehensive loss |
|
|
$ |
(25,424 |
) |
|
$ |
(7,522 |
) |
|
$ |
(44,619 |
) |
|
$ |
(15,568 |
) |
See accompanying notes to unaudited condensed consolidated financial statements.
3
CONDENSED CONSOLIDATED STATEMENTS OF STOCKHOLDERS’ EQUITY
(In thousands)
(Unaudited)
|
|
Common Stock |
|
|
Additional Paid-In |
|
|
Other Comprehensive |
|
|
Accumulated |
|
|
Total Stockholders' |
|
|||||||||
|
|
Shares |
|
|
Amount |
|
|
Capital |
|
|
Gain (Loss) |
|
|
Deficit |
|
|
Equity |
|
||||||
Balance at December 31, 2019 |
|
|
66,886 |
|
|
$ |
67 |
|
|
$ |
526,771 |
|
|
$ |
25 |
|
|
$ |
(196,144 |
) |
|
$ |
330,719 |
|
Issuance of common stock upon exercise of stock options |
|
|
984 |
|
|
|
1 |
|
|
|
3,590 |
|
|
|
— |
|
|
|
— |
|
|
|
3,591 |
|
Vesting of common stock from early exercises |
|
|
21 |
|
|
|
— |
|
|
|
162 |
|
|
|
— |
|
|
|
— |
|
|
|
162 |
|
Stock-based compensation expense |
|
|
— |
|
|
|
— |
|
|
|
3,695 |
|
|
|
— |
|
|
|
— |
|
|
|
3,695 |
|
Changes in unrealized loss on available-for-sale securities |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(80 |
) |
|
|
— |
|
|
|
(80 |
) |
Net loss |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(19,115 |
) |
|
|
(19,115 |
) |
Balance at March 31, 2020 |
|
|
67,891 |
|
|
$ |
68 |
|
|
$ |
534,218 |
|
|
$ |
(55 |
) |
|
$ |
(215,259 |
) |
|
$ |
318,972 |
|
Issuance of common stock upon exercise of stock options |
|
|
680 |
|
|
|
1 |
|
|
|
2,365 |
|
|
|
— |
|
|
|
— |
|
|
|
2,366 |
|
Issuance of common stock in connection with employee stock purchase plan |
|
|
109 |
|
|
|
— |
|
|
|
1,285 |
|
|
|
— |
|
|
|
— |
|
|
|
1,285 |
|
Issuance of common stock under 401(k) Plan |
|
|
6 |
|
|
|
— |
|
|
|
119 |
|
|
|
— |
|
|
|
— |
|
|
|
119 |
|
Vesting of common stock from early exercises |
|
|
16 |
|
|
|
— |
|
|
|
123 |
|
|
|
— |
|
|
|
— |
|
|
|
123 |
|
Stock-based compensation expense |
|
|
— |
|
|
|
— |
|
|
|
3,723 |
|
|
|
— |
|
|
|
— |
|
|
|
3,723 |
|
Changes in unrealized gain on available-for-sale securities |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
192 |
|
|
|
— |
|
|
|
192 |
|
Net loss |
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(25,616 |
) |
|
|
(25,616 |
) |
Balance at June 30, 2020 |
|
|
68,702 |
|
|
$ |
69 |
|
|
$ |
541,833 |
|
|
$ |
137 |
|
|
$ |
(240,875 |
) |
|
$ |
301,164 |
|
See accompanying notes to unaudited condensed consolidated financial statements.
4
CONDENSED CONSOLIDATED STATEMENTS OF CONVERTIBLE PREFERRED STOCK
AND STOCKHOLDERS’ EQUITY (DEFICIT)
(Unaudited)
(In Thousands)
|
|
Convertible Preferred Stock |
|
|
|
Common Stock(1) |
|
|
Additional Paid-In |
|
|
Other Comprehensive |
|
|
Accumulated |
|
|
Total Stockholders' |
|
||||||||||||||
|
|
Shares |
|
|
Amount |
|
|
|
Shares |
|
|
Amount |
|
|
Capital |
|
|
Gain (Loss) |
|
|
Deficit |
|
|
Equity(Deficit) |
|
||||||||
Balance at December 31, 2018 |
|
|
47,267 |
|
|
$ |
294,874 |
|
|
|
|
6,733 |
|
|
$ |
7 |
|
|
$ |
39,258 |
|
|
$ |
(267 |
) |
|
$ |
(147,193 |
) |
|
$ |
(108,195 |
) |
Issuance of common stock upon exercise of stock options |
|
|
— |
|
|
|
— |
|
|
|
|
80 |
|
|
|
— |
|
|
|
279 |
|
|
|
— |
|
|
|
— |
|
|
|
279 |
|
Issuance of common stock under 401(k) Plan |
|
|
— |
|
|
|
— |
|
|
|
|
8 |
|
|
|
— |
|
|
|
98 |
|
|
|
— |
|
|
|
— |
|
|
|
98 |
|
Vesting of common stock from early exercises |
|
|
— |
|
|
|
— |
|
|
|
|
34 |
|
|
|
— |
|
|
|
237 |
|
|
|
— |
|
|
|
— |
|
|
|
237 |
|
Stock-based compensation expense |
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
— |
|
|
|
2,605 |
|
|
|
— |
|
|
|
— |
|
|
|
2,605 |
|
Changes in unrealized gain on available-for-sale securities |
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
222 |
|
|
|
— |
|
|
|
222 |
|
Net exercise of preferred stock warrant to Series A preferred stock |
|
|
16 |
|
|
|
198 |
|
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
Cumulative effect adjustment upon adoption of ASU 2014-09 |
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(6,156 |
) |
|
|
(6,156 |
) |
Net loss |
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(8,268 |
) |
|
|
(8,268 |
) |
Balance at March 31, 2019 |
|
|
47,283 |
|
|
$ |
295,072 |
|
|
|
|
6,855 |
|
|
$ |
7 |
|
|
$ |
42,477 |
|
|
$ |
(45 |
) |
|
$ |
(161,617 |
) |
|
$ |
(119,178 |
) |
Conversion of Series A, B, C, D, E convertible preferred stock to common stock concurrent with initial public offering |
|
|
(47,283 |
) |
|
|
(295,072 |
) |
|
|
|
47,283 |
|
|
|
47 |
|
|
|
295,025 |
|
|
|
— |
|
|
|
— |
|
|
|
295,072 |
|
Issuance of common stock upon initial public offering, net of issuance cost |
|
|
— |
|
|
|
— |
|
|
|
|
7,521 |
|
|
|
8 |
|
|
|
107,748 |
|
|
|
— |
|
|
|
— |
|
|
|
107,756 |
|
Issuance of common stock upon private placement |
|
|
— |
|
|
|
— |
|
|
|
|
4,122 |
|
|
|
4 |
|
|
|
65,943 |
|
|
|
— |
|
|
|
— |
|
|
|
65,947 |
|
Issuance of common stock upon exercise of stock options |
|
|
— |
|
|
|
— |
|
|
|
|
86 |
|
|
|
— |
|
|
|
258 |
|
|
|
— |
|
|
|
— |
|
|
|
258 |
|
Vesting of common stock from early exercises |
|
|
— |
|
|
|
— |
|
|
|
|
32 |
|
|
|
— |
|
|
|
245 |
|
|
|
— |
|
|
|
— |
|
|
|
245 |
|
Stock-based compensation expense |
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
— |
|
|
|
3,552 |
|
|
|
— |
|
|
|
— |
|
|
|
3,552 |
|
Changes in unrealized gain on available-for-sale securities |
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
147 |
|
|
|
— |
|
|
|
147 |
|
Net loss |
|
|
— |
|
|
|
— |
|
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
— |
|
|
|
(7,669 |
) |
|
|
(7,669 |
) |
Balance at June 30, 2019 |
|
|
— |
|
|
|
— |
|
|
|
|
65,899 |
|
|
$ |
66 |
|
|
$ |
515,248 |
|
|
$ |
102 |
|
|
$ |
(169,286 |
) |
|
$ |
346,130 |
|
(1) |
In April 2019, the Company completed its initial public offering (“IPO”) and concurrent private placement with Merck Sharp & Dohme Corp. (“Merck”), in which the Company issued an aggregate of 7,521,394 and 4,121,683 shares of common stock, respectively, for net proceeds of $107.8 million and $65.9 million, respectively. Upon the closing of the IPO, all of the then outstanding shares of convertible preferred stock were automatically converted into shares of common stock and its related carrying amount of $295.1 million was reclassified to common stock and additional paid-in-capital. |
See accompanying notes to unaudited condensed consolidated financial statements.
5
CONDENSED CONSOLIDATED STATEMENTS OF CASH FLOWS
(Unaudited)
(In Thousands)
|
|
Six Months Ended |
|
|||||
|
|
June 30, |
|
|||||
|
|
2020 |
|
|
2019 |
|
||
Cash flows from operating activities |
|
|
|
|
|
|
|
|
Net loss |
|
$ |
(44,731 |
) |
|
$ |
(15,937 |
) |
Adjustments to reconcile net loss to net cash used in operating activities: |
|
|
|
|
|
|
|
|
Depreciation |
|
|
3,381 |
|
|
|
3,896 |
|
Amortization of discount on marketable securities |
|
|
(190 |
) |
|
|
(803 |
) |
Stock-based compensation expense |
|
|
7,418 |
|
|
|
6,157 |
|
Other non-cash expenses |
|
|
239 |
|
|
|
217 |
|
Changes in operating assets and liabilities: |
|
|
|
|
|
|
|
|
Related party receivable from collaboration |
|
|
2,127 |
|
|
|
2,788 |
|
Prepaid expenses and other assets |
|
|
(3,119 |
) |
|
|
(1,864 |
) |
Accounts payable |
|
|
(6,874 |
) |
|
|
(2,511 |
) |
Accrued expenses and other liabilities |
|
|
7,634 |
|
|
|
1,167 |
|
Deferred rent |
|
|
(1,378 |
) |
|
|
(1,305 |
) |
Deferred revenue |
|
|
(2,798 |
) |
|
|
(11,682 |
) |
Net cash used in operating activities |
|
|
(38,291 |
) |
|
|
(19,877 |
) |
Cash flows from investing activities |
|
|
|
|
|
|
|
|
Purchase of marketable securities |
|
|
(29,399 |
) |
|
|
(75,224 |
) |
Proceeds from sales and maturities of marketable securities |
|
|
65,836 |
|
|
|
128,990 |
|
Purchase of property and equipment |
|
|
(1,445 |
) |
|
|
(2,275 |
) |
Net cash provided by investing activities |
|
|
34,992 |
|
|
|
51,491 |
|
Cash flows from financing activities |
|
|
|
|
|
|
|
|
Proceeds from issuance of common stock upon initial public offering, net of issuance costs |
|
|
— |
|
|
|
110,078 |
|
Proceeds from issuance of common stock upon completion of private placement |
|
|
— |
|
|
|
65,947 |
|
Proceeds from issuance of common stock upon exercise of stock options |
|
|
5,957 |
|
|
|
510 |
|
Proceeds from issuance of common stock in connection with employee stock purchase plan |
|
|
1,285 |
|
|
|
— |
|
Payments of deferred financing costs |
|
|
(224 |
) |
|
|
— |
|
Net cash provided by financing activities |
|
|
7,018 |
|
|
|
176,535 |
|
Net increase in cash and cash equivalents |
|
|
3,719 |
|
|
|
208,149 |
|
Cash, cash equivalents and restricted cash at beginning of period |
|
|
247,472 |
|
|
|
59,172 |
|
Cash, cash equivalents and restricted cash at end of period |
|
$ |
251,191 |
|
|
$ |
267,321 |
|
|
|
|
|
|
|
|
|
|
Non-cash investing and financing activities: |
|
|
|
|
|
|
|
|
Net exercise of convertible preferred stock warrant to Series A preferred stock |
|
$ |
— |
|
|
$ |
198 |
|
Vesting of common stock from early exercises |
|
|
285 |
|
|
|
482 |
|
Cost of property and equipment purchases accrued but not yet paid |
|
|
87 |
|
|
|
128 |
|
Deferred offering costs accrued but not yet paid |
|
|
235 |
|
|
|
30 |
|
See accompanying notes to unaudited condensed consolidated financial statements.
6
NOTES TO UNAUDITED CONDSENSED CONSOLIDATED FINANCIAL STATEMENTS
1. Organization and Description of Business
NGM Biopharmaceuticals, Inc. and its wholly-owned subsidiary (collectively, referred to as the “Company”) is a biopharmaceutical company focused on discovering and developing novel therapeutics based on scientific understanding of key biological pathways underlying liver, retinal and metabolic diseases and cancer. The five most advanced proprietary product candidates in the Company’s portfolio are aldafermin (NGM282), NGM313, NGM621, NGM120 and NGM395.
The Company was incorporated in Delaware in December 2007 and commenced operations in 2008. Its headquarters are located at 333 Oyster Point Blvd., South San Francisco, California 94080.
2. Summary of Significant Accounting Policies
Basis of Presentation and Principles of Consolidation
The accompanying unaudited condensed consolidated financial statements have been prepared in accordance with generally accepted accounting principles in the United States of America (“U.S. GAAP”) and Regulation S-X for interim consolidated financial information. These unaudited condensed consolidated financial statements should be read in conjunction with the audited consolidated financial statements and notes for the year ended December 31, 2019 included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2019 filed with the United States Securities and Exchange Commission (“SEC”) on March 17, 2020 (the “Annual Report”). These unaudited condensed consolidated financial statements reflect all adjustments that management believes are necessary for a fair presentation of the periods presented. All such adjustments are of a normal recurring nature and are not necessarily indicative of results expected for the full fiscal year or for any subsequent interim period.
These unaudited condensed consolidated financial statements include the consolidated accounts of the Company and its wholly-owned foreign subsidiary in Australia. All intercompany balances and transactions have been eliminated upon consolidation.
Use of Estimates
The preparation of condensed consolidated financial statements in conformity with U.S. GAAP requires management to make judgments, assumptions and estimates that affect the reported amounts of assets, liabilities, revenues and expenses. Specific accounts that require management estimates include, but are not limited to, the valuation of common stock and the associated stock-based compensation expense, contract manufacturing accruals, clinical trial accruals and revenue recognition in accordance with Accounting Standards Codification 606 (“ASC 606”). Management bases its estimates on historical experience and on various other assumptions that are believed to be reasonable under the circumstances, the results of which form the basis for making judgments about the carrying value of assets and liabilities that are not readily apparent from other sources. Actual results could differ materially from those estimates.
Need for Additional Capital
Since inception, the Company has incurred net losses and negative cash flow from operations. During the three and six months ended June 30, 2020, the Company incurred net losses of $25.6 million and $44.7 million, respectively, compared to $7.7 million and $15.9 million, respectively, for the three and six months ended June 30, 2019. As of June 30, 2020, the Company had an accumulated deficit of $240.9 million and does not expect to experience positive cash flows from operations in the near future. The Company had $312.1 million of cash, cash equivalents and marketable securities as of June 30, 2020, and therefore the Company expects that its cash, cash equivalents and marketable securities will be sufficient to fund its operations for a period of at least one year from the date these unaudited condensed consolidated financial statements are available for issuance. The Company plans to continue to fund its operations and pursue its strategy through public or private equity or debt financings, government or other third-party funding, collaborations, strategic alliances and licensing arrangements or a combination of these.
7
In June 2020, the Company filed a registration statement on Form S-3 and entered into an Open Market Sale AgreementSM (“Sales Agreement”) with Jefferies LLC (“Jefferies”) pursuant to which the Company may elect to issue and sell, from time to time, shares of common stock having an aggregate offering price of up to $150.0 million through Jefferies acting as the sales agent and/or principal. Offering costs incurred in connection with the Company’s registration statement on Form S-3 and execution of the Sales Agreement with Jefferies primarily consist of legal, printing and accounting fees. Offering costs are capitalized as incurred and will be offset against proceeds received from future offerings or issuances under the registration statement on Form S-3 on a pro‑rata basis. No shares of common stock have been sold pursuant to the Sales Agreement as of June 30, 2020. As of June 30, 2020 and December 31, 2019, there were $0.5 million and zero, respectively, of deferred offering costs included within other non-current assets on the condensed consolidated balance sheets.
Fair Value of Financial Instruments
The carrying amounts of cash and cash equivalents, receivables from collaborations, the related party receivables from collaboration and other current assets and liabilities approximate their respective fair values because of the short-term nature of those instruments.
Cash and Cash Equivalents
Cash and cash equivalents are stated at fair value. Cash equivalents are securities with an original maturity of three months or less at the time of purchase. The Company limits its credit risk associated with cash and cash equivalents by placing its investments with a bank it believes is highly creditworthy and with highly rated money market funds. As of June 30, 2020 and December 31, 2019, cash and cash equivalents consisted of bank deposits and investments in money market funds.
Marketable Securities
The appropriate classification of the Company’s marketable securities is determined at the time of purchase and such designations are re-evaluated at each balance sheet date. All of the Company’s securities are considered available-for-sale, carried at estimated fair values and reported in cash equivalents, short-term marketable securities or long-term marketable securities. Unrealized gains and losses on available-for-sale securities are excluded from net loss and reported in accumulated other comprehensive loss as a separate component of stockholders’ equity. Other income (expense), net, includes interest, amortization of purchase premiums and accretion of purchase discounts, realized gains and losses on sales of securities and other-than-temporary declines in the fair value of securities, if any. The cost of securities sold is based on the specific identification method.
The Company’s investments are regularly reviewed for other-than-temporary declines in fair value. This review includes the consideration of the cause of the impairment, including the creditworthiness of the security issuers, the number of securities in an unrealized loss position, the severity and duration of the unrealized losses, whether the Company has the intent to sell the securities and whether it is more likely than not that the Company will be required to sell the securities before the recovery of their amortized cost basis. When the Company determines that the fair value of an investment is below its carrying value and this decline is other-than-temporary, the Company reduces the carrying value of the security it holds and records a loss for the amount of such decline. As of June 30, 2020, the Company did not record any impairment related to other-than-temporary declines in the fair value of securities.
Restricted Cash
The Company’s restricted cash represents collateral in connection with the lease on the Company’s headquarters entered into in 2015 and is classified as a non-current asset on the condensed consolidated balance sheets as the collateral will not be returned to the Company in less than 12 months (Note 6).
8
Concentration of Credit and Other Risks
Cash and cash equivalents and marketable securities from the Company’s available-for-sale and marketable security portfolio potentially subject the Company to concentrations of credit risk. The Company is invested in money market funds and marketable securities through custodial relationships with major U.S. and Australian banks. Under its investment policy, the Company limits amounts invested in such securities by credit rating, maturity, industry group, investment type and issuer, except for securities issued by the U.S. government.
Related party receivables from collaborations (Note 5) are typically unsecured. Accordingly, the Company may be exposed to credit risk generally associated with its Research Collaboration, Product Development and License Agreement with Merck (“Collaboration Agreement”). To date, the Company has not experienced any losses related to these receivables.
Merck accounted for 100% of the Company’s revenue for the three and six months ended June 30, 2020 and 2019.
Property and Equipment, Net
Property and equipment is recorded at cost and consists of computer equipment, laboratory equipment and office furniture and leasehold improvements. Maintenance and repairs, and training on the use of equipment, are expensed as incurred. Costs that improve assets or extend their economic lives are capitalized. Depreciation is recognized using the straight-line method based on an estimated useful life of the asset, which is as follows:
Computer equipment |
3 years |
Laboratory equipment and office furniture |
3 years |
Leasehold improvement |
Shorter of life of asset or lease term |
Leases
The Company’s lease agreements for its laboratory and office facilities are classified as operating leases. Rent expense is recognized on a straight-line basis over the term of the applicable lease. Incentives granted under the Company’s facilities leases, including allowances to fund leasehold improvements and rent holidays, are capitalized and are recognized as reductions to rental expense on a straight-line basis over the term of the applicable lease.
Impairment of Long-Lived Assets
Long-lived assets, such as property and equipment, are reviewed for impairment whenever events or changes in circumstances indicate that the carrying amount of an asset may not be recoverable. Recoverability of assets to be held and used is measured by a comparison of the carrying amount of an asset to the estimated undiscounted future cash flows expected to be generated by the asset. If the carrying amount of an asset exceeds its estimated undiscounted future cash flows, an impairment charge is recognized as the amount by which the carrying amount of the asset exceeds the estimated fair value of the asset. As of June 30, 2020 and December 31, 2019, no revision to the remaining useful lives or write-down of long-lived assets was required.
Income Taxes
Income taxes are accounted for under the liability method. Deferred tax assets and liabilities are recognized for the future tax consequences attributable to the differences between the financial statement carrying amounts of existing assets and liabilities and their respective tax bases and the operating loss and tax credit carryforwards. Valuation allowances are established when necessary to reduce deferred tax assets to the amount expected to be realized. Deferred tax assets and liabilities are measured at the balance sheet date using the enacted tax rates expected to apply to taxable income in the years in which those temporary differences are expected to be recovered or settled. The effect on deferred tax assets and liabilities of a change in tax rates is recognized in the period such tax rate changes are enacted.
9
The Company adopted Accounting Standards Update (“ASU”) 2014-09, Revenue from Contracts with Customers (Topic 606), and subsequent amendments, on January 1, 2019. ASC 606 requires an entity to recognize revenue upon the transfer of goods or services to customers in an amount that reflects the consideration to which the entity expects to be entitled in exchange for those goods or services. The Company applies the following five-step revenue recognition model outlined in ASC 606 to adhere to this core principle: (1) identify the contract(s) with a customer; (2) identify the performance obligations in the contract; (3) determine the transaction price; (4) allocate the transaction price to the performance obligations in the contract; and (5) recognize revenue when (or as) the Company satisfies a performance obligation.
All of the Company’s revenue to date has been generated from its collaboration agreements, primarily with Merck. The terms of these agreements generally require the Company to provide (i) license options for its compounds, (ii) research and development services and (iii) non-mandatory services in connection with participation in research or steering committees. Payments received under these arrangements may include non-refundable upfront license fees, partial or complete reimbursement of research and development costs, contingent consideration payments based on the achievement of defined collaboration objectives and royalties on sales of commercialized products. In some agreements, the collaboration partner is solely responsible for meeting defined objectives that trigger contingent or royalty payments. Often the partner only pursues such objectives subsequent to exercising an optional license on compounds identified as a result of the research and development services performed under the collaboration agreement.
The Company assesses whether the promises in its arrangements, including any options provided to the partner, are considered distinct performance obligations that should be accounted for separately. Judgment is required to determine whether the license to a compound is distinct from research and development services or participation in research or steering committees, as well as whether options create material rights in the contract.
The transaction price in each arrangement is generally comprised of a non-refundable upfront fee and unconstrained variable consideration related to the performance of research and development services. The Company typically submits a budget for the research and development services to the partner in advance of performing the services. The transaction price is allocated to the identified performance obligations based on the standalone selling price (“SSP”) of each distinct performance obligation. Judgment is required to determine the SSP. In instances where the SSP is not directly observable, such as when a license or service is not sold separately, SSP is determined using information that may include market conditions and other observable inputs. The Company utilizes judgment to assess the nature of its performance obligations to determine whether they are satisfied over time or at a point in time and, if over time, the appropriate method of measuring progress toward completion. The Company evaluates the measure of progress each reporting period and, if necessary, adjusts the measure of performance and related revenue recognition.
The Company’s collaboration agreements may include contingent payments related to specified development and regulatory milestones or contingent payments for royalties based on sales of a commercialized product. Milestones can be achieved for such activities in connection with progress in clinical trials, regulatory filings in various geographical markets and marketing approvals from regulatory authorities. Sales-based royalties are generally related to the volume of annual sales of a commercialized product. At the inception of each agreement that includes such payments, the Company evaluates whether the milestones are considered probable of being achieved and estimates the amount to be included in the transaction price by using the most likely amount method. If it is probable that a significant revenue reversal would not occur, the associated milestone value is included in the transaction price. Milestone payments that are not within the Company’s or its partner’s control, such as those related to regulatory approvals, are not considered probable of being achieved until those approvals are received. The transaction price is then allocated to each performance obligation based on a relative SSP basis. At the end of each subsequent reporting period, the Company re-evaluates the probability of achievement of each such milestone and any related constraint and, if necessary, adjusts its estimate of the overall transaction price. Pursuant to the guidance in ASC 606, sales-based royalties are not included in the transaction price. Instead, royalties are recognized at the later of when the performance obligation is satisfied or partially satisfied, or when the sale that gives rise to the royalty occurs.
10
Research and development costs are expensed as incurred. Research and development expenses primarily include salaries and benefits for medical, clinical, quality, preclinical, manufacturing and research personnel, costs related to research activities, preclinical studies, clinical trials, drug manufacturing expenses and allocated overhead and facility occupancy costs. The Company accounts for non-refundable advance payments for goods or services that will be used in future research and development activities as expenses when the goods have been received or when the service has been performed rather than when the payment is made.
Clinical trial costs are a component of research and development expenses. The Company expenses costs for its clinical trial activities performed by third parties, including clinical research organizations (“CROs”) and other service providers, as they are incurred, based upon estimates of the work completed over the life of the individual study in accordance with associated agreements. The Company uses information it receives from internal personnel and outside service providers to estimate the clinical trial costs incurred.
Stock-Based Compensation
The Company’s stock-based compensation programs include stock options and shares issued under the Company’s 2019 Employee Stock Purchase Plan (“ESPP”). Stock-based compensation to employees is valued on the grant date of each award using the Black-Scholes option-pricing model, and its estimated fair value is recognized over the period during which the employee is required to provide services in exchange for the award, which is generally the vesting period of each award. Stock-based compensation expense for non-employee stock-based awards is also measured based on the fair value on grant date with its estimated fair value recorded over the period for which the non-employee is required to provide services in exchange for the award. As non-cash stock-based compensation expense is based on awards ultimately expected to vest, it is reduced by an estimate for future forfeitures. Forfeitures are estimated at the time of grant and revised, if necessary, in subsequent periods if actual forfeitures materially differ from estimates.
Foreign Currency Transactions
The functional currency of NGM Biopharmaceuticals Australia Pty Ltd., the Company’s wholly-owned subsidiary, is the U.S. Dollar. Accordingly, all monetary assets and liabilities of the subsidiary are remeasured into U.S. Dollars at the current period-end exchange rates and non-monetary assets are remeasured using historical exchange rates. Income and expense elements are remeasured to U.S. Dollars using the average exchange rates in effect during the period. Remeasurement gains and losses are recorded as other income (expense), net on the consolidated statements of operations.
The Company is subject to foreign currency risk with respect to its clinical and manufacturing contracts denominated in currencies other than the U.S. Dollar, primarily British Pounds, Swiss Francs, Australian Dollars and the Euro. Payments on contracts denominated in foreign currencies are made at the spot rate on the day of payment. Changes in the exchange rate between billing dates and payment dates are recorded within other income (expense), net, on the condensed consolidated statements of operations.
Comprehensive Loss
Comprehensive loss is comprised of net loss and certain changes in equity that are excluded from net loss. For the three and six months ended June 30, 2020, the difference between comprehensive loss and net loss consisted of changes in net unrealized gain on available-for-sale marketable securities of $0.2 million and $0.1 million, respectively, compared to $0.2 million and $0.4 million for the three and six months ended June 30, 2019, respectively.
11
Basic net loss per share is calculated by dividing net loss by the weighted average number of shares outstanding during the period, less shares subject to repurchase, and excludes any dilutive effects of stock-based awards and warrants. Diluted net loss per share is computed giving effect to all potentially dilutive shares, including common stock issuable upon exercise of stock options, shares committed under the ESPP and unvested restricted common stock and stock units. As the Company incurred net losses for the three and six months ended June 30, 2020 and 2019, all potential common shares were determined to be anti-dilutive and have been excluded in the diluted net loss per share calculations.
The following table sets forth the computation of net loss per common share (in thousands, except share and per share amounts):
|
|
Three Months Ended |
|
|
Six Months Ended |
||||||||||||
|
|
June 30, |
|
|
June 30, |
||||||||||||
|
|
2020 |
|
|
2019 |
|
|
2020 |
|
|
2019 |
|
|
||||
Numerator: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Net loss |
|
$ |
(25,616 |
) |
|
$ |
(7,669 |
) |
|
$ |
(44,731 |
) |
|
$ |
(15,937 |
) |
|
Denominator: |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Weighted average number of shares used in calculating net loss per share—basic and diluted |
|
|
68,305,056 |
|
|
|
61,044,450 |
(1) |
|
|
67,850,640 |
|
|
|
34,078,099 |
|
|
Net loss per share—basic and diluted |
|
$ |
(0.38 |
) |
|
$ |
(0.13 |
) |
|
$ |
(0.66 |
) |
|
$ |
(0.47 |
) |
|
(1) |
In April 2019, the Company completed its IPO and concurrent private placement with Merck, in which the Company issued an aggregate of 7,521,394 and 4,121,683 shares of common stock, respectively, and all of the then outstanding shares of convertible preferred stock were automatically converted into shares of common stock upon the closing of the IPO. |
Potentially dilutive securities that were not included in the diluted net loss per share calculations because they would be anti-dilutive were as follows:
|
|
Six Months Ended |
|||||||
|
|
June 30, |
|
|
|||||
|
|
2020 |
|
|
2019 |
|
|
||
Options to purchase common stock |
|
|
10,478,682 |
|
|
|
11,417,124 |
|
|
Shares committed under ESPP |
|
|
467,614 |
|
|
|
406,200 |
|
|
Total |
|
|
10,946,296 |
|
|
|
11,823,324 |
|
|
Segment and Geographical Information
The Company operates in one business segment. Substantially all of the Company’s long-lived assets, comprised of property and equipment, are based in the United States. For the three and six months ended June 30, 2020 and 2019, the Company’s revenues were entirely within the United States based upon the location of its partner.
Recent Accounting Pronouncements
New accounting pronouncements are issued by the Financial Accounting Standards Board (“FASB”) or other standard setting bodies and adopted by the Company as of the specified effective date. Unless otherwise discussed, the impact of recently issued standards that are not yet effective will not have a material impact on our condensed consolidated financial statements upon adoption. Under the Jumpstart Our Business Startups Act of 2012, as amended (the “JOBS Act”), the Company meets the definition of an emerging growth company, and has elected the extended transition period for complying with new or revised accounting standards pursuant to Section 107(b) of the JOBS Act.
12
Recently Adopted Accounting Pronouncements
In August 2018, the FASB issued ASU 2018-13, Fair Value Measurements (Topic 820): Disclosure Framework – Changes to the Disclosure Requirements for Fair Value Measurement, as part of the FASB’s disclosure framework project. ASU 2018-13 modifies the disclosure requirements on fair value measurements in Topic 820, Fair Value Measurements by removing the requirement to disclose amounts of and reasons for transfers between Level 1 and Level 2 of the fair value hierarchy, the policy for timing of transfers between levels and the valuation process for Level 3 fair value measurements. ASU 2018-13 also modifies existing disclosure requirements by clarifying that the measurement uncertainty disclosure is to communicate information about the uncertainty in measurement as of the reporting date, and adds required disclosures for the changes in unrealized gains and losses for the period included in other comprehensive income for recurring Level 3 fair value measurements held at the end of the reporting period and the range and weighted average of significant unobservable inputs used to develop Level 3 fair value measurements. The Company adopted ASU 2018-13 effective January 1, 2020, noting no material impact on the Company’s condensed consolidated financial statements.
Recent Accounting Pronouncements Not Yet Adopted
In February 2016, the FASB issued ASU 2016-02, Leases (Topic 842), which increases lease transparency and comparability among organizations. Under the new standard, lessees will be required to recognize right-of-use (“ROU”) assets and lease liabilities arising from lease arrangements on the consolidated balance sheets, with the exception of leases with a term of 12 months or less, which permits a lessee to make an accounting policy election by class of underlying asset not to recognize the ROU assets and lease liabilities. In March 2018, the FASB approved an alternative transition method to the modified retrospective approach, which eliminates the requirement to restate prior period condensed consolidated financial statements and allows the cumulative effect of the retrospective allocation to be recorded as an adjustment to the opening balance of retained earnings at the date of adoption. In November 2019, the FASB issued ASU 2019-10, which deferred the effective date for certain ASUs including ASU 2016-02. In June 2020, due to the evolving impacts of the COVID-19 pandemic, the FASB issued ASU 2020-05, which further defers the effective date of ASU 2016-02. The new guidance is now effective for the Company’s fiscal year beginning after December 15, 2021, and interim periods within fiscal years beginning after December 15, 2022. Early adoption continues to be permitted for all entities.
The Company plans to adopt the new lease standard in accordance with the new guidance, in the fiscal year beginning after December 15, 2021, using the optional transition method, which allows the Company to recognize a cumulative-effect adjustment to the opening balance of accumulated deficit at the date of adoption and apply the new disclosure requirements beginning in the period of adoption. The Company also plans to elect the package of practical expedients permitted under the transition guidance within the new standard, which, among other things, allows the Company to carryforward the historical lease classification and make an accounting policy election whereby ROU assets and lease liabilities associated with lease arrangements with terms less than one year will not be recognized. We will continue to evaluate the effect that this guidance will have on our condensed consolidated financial statements.
In June 2016, the FASB issued ASU 2016-13, Financial Instruments – Credit Losses (Topic 326): Measurement of Credit Losses on Financial Instruments. The new standard amends guidance on reporting credit losses for financial assets held at amortized cost basis, including accounts receivable, investments classified as available for sale, such as our debt securities, and unbilled related party revenue. Estimated credit losses will be recorded as an allowance rather than a write-down. In November 2019, the FASB issued ASU 2019-10, which deferred the effective date for certain ASUs including ASU 2016-13. This standard is now effective for the Company’s fiscal year beginning after December 15, 2022. Early adoption is permitted for all entities. The Company is currently assessing the timing of adoption and the impact that the adoption of ASU 2016-13 will have on its condensed consolidated financial statements.
13
In November 2018, the FASB issued ASU 2018-18, Collaborative Arrangements (ASC 808): Clarifying the Interaction between ASC 808 and ASC 606, which clarifies that certain transactions between collaborative arrangement participants should be accounted for as revenue under ASC 606 when the collaborative arrangement participant is a customer in the context of a unit of account. In those situations, all the guidance in ASC 606 should be applied, including recognition, measurement and presentation and disclosure requirements. ASU 2018-18 adds unit-of-account guidance in ASC 808 to align with the guidance in ASC 606 (that is, a distinct good or service) when an entity is assessing whether the collaborative arrangement or a part of the arrangement is within the scope of ASC 606, and requires that in a transaction with a collaborative arrangement participant that is not directly related to sales to third parties, presenting the transaction together with revenue recognized under ASC 606 is precluded if the collaborative arrangement participant is not a customer. ASU 2018-18 will be effective for the Company’s fiscal year beginning after December 15, 2020, and interim periods within fiscal years beginning after December 15, 2021. The Company is currently assessing the timing of adoption and the impact that the adoption of ASU 2018-18 will have on its condensed consolidated financial statements.
In December 2019, the FASB issued ASU 2019-12, Income Taxes (Topic 740): Simplifying the Accounting for Income Taxes. The new guidance modifies ASC 740 to simplify several aspects of accounting for income taxes, including eliminating certain exceptions to the guidance in ASC 740 related to the approach for intraperiod tax allocation. ASU 2019-12 will be effective for the Company for fiscal year beginning after December 15, 2021, and interim periods within fiscal year beginning after December 15, 2022, and is required to be adopted prospectively, with the exception of certain specific amendments. The Company is currently assessing the timing of adoption and the impact that the adoption of ASU 2019‑12 will have on its condensed consolidated financial statements.
3. Fair Value Measurements
Financial assets and liabilities are recorded at fair value. The carrying amount of certain financial instruments, including cash and cash equivalents, receivable from collaboration, related party receivable from collaboration and other current assets and liabilities approximate fair value due to their relatively short maturities. Assets and liabilities recorded at fair value on a recurring basis in the balance sheets are categorized based upon the level of judgment associated with the inputs used to measure their fair values. Fair value accounting is applied to the convertible preferred stock warrant liabilities that are recorded at their estimated fair value in the condensed consolidated financial statements.
The FASB has defined fair value as the exchange price that would be received for an asset or paid to transfer a liability, or an exit price, in the principal or most advantageous market for that asset or liability in an orderly transaction between market participants on the measurement date, and established a fair value hierarchy that requires an entity to maximize the use of observable inputs, where available, and minimize the use of unobservable inputs when measuring fair value. The FASB set forth three levels of inputs that may be used to measure fair value:
Level 1: Quoted prices in active markets for identical assets or liabilities.
Level 2: Observable inputs other than Level 1 prices, such as quoted prices for similar assets or liabilities, quoted prices in markets that are not active, or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.
Level 3: Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.
Assets and liabilities measured at fair value are classified in their entirety based on the lowest level of input that is significant to the fair value measurement. The Company’s assessment of the significance of a particular input to the fair value measurement in its entirety requires management to make judgments and consider factors specific to the asset or liability.
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To date, the Company has not recorded any impairment charges against the market value of its marketable securities. In determining whether a decline is other than temporary, the Company considers various factors including the length of time and extent to which the market value has been less than cost, the financial condition and near-term prospects of the issuer and the Company’s intent and ability to retain its investment in the issuer for a period of time sufficient to allow for any anticipated recovery in market value.
The Company estimates the fair values of investments in corporate agency bond securities, commercial paper and government agencies securities using Level 2 inputs by taking into consideration valuations obtained from third-party pricing services. The pricing services utilize industry standard valuation models, including both income and market-based approaches, for which all significant inputs are observable, either directly or indirectly, to estimate fair value. These inputs include reported trades of and broker/dealer quotes on the same or similar securities, issuer credit spreads, benchmark securities, prepayment/default projections based on historical data and other observable inputs.
Cash and cash equivalents and marketable securities, all of which are classified as available-for-sale securities, consisted of the following (in thousands):
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Amortized Cost |
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Gross Unrealized Gain |
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Gross Unrealized Loss |
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Fair Value |
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As of June 30, 2020 |
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Money market funds |
|
$ |
247,026 |
|
|
$ |
— |
|
|
$ |
— |
|
|
$ |
247,026 |
|
Corporate and agency bonds |
|
|
34,089 |
|
|
|
137 |
|
|
|
— |
|
|
|
34,226 |